The first and second editions of this book were conceived to provide distilled, up-to-date information to nursing students and staff nurses about many conditions and diagnoses encountered in nursing practice. With the third edition, we have responded to the ever-changing health care environment as well as to the recommendations of our readers and editors. We have held true to our initial purpose in this third edition: to provide a ready source of information for nurses in a time of short staffing, brief lengths of stay, and increasing patient acuity in the hospital, in nursing homes, in rehabilitation centers, and in the home. We have also responded to the everincreasing need for nurses to understand the scientific basis of their practice by augmenting the pathophysiology sections that were in the past two editions.
Perhaps the most significant addition to the third edition is a section entitled Genetic Considerations. Since the completion of the Human Genome Project in 2003, the health care disciplines are beginning to understand the enormous significance of the human genome sequence, which provides foundational information that shows us how genes and proteins work together to promote human health. This section of the book assists practitioners to consider how the genetic basis of disease is related to environmental factors in health and disease, and how disease susceptibility, detection of illness, and drug response are related to people’s genetic make-up. We are indebted to co-author Dr. Terry Beery for the development of the genetic information contained in this edition.

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